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Algae bio-reactive building envelopes (ABBEs) are self-adaptive shading systems that integrate an algae bioreactor technology to regulate natural lighting and heat in buildings, while also allowing for energy harvest and CO2capture. In this paper, ABBEs are proposed and supported through experiments and computer simulations. Using experiments, we investigate how the algae bioreactor will self-adjust in response to environmental factors. Through simulations, we analyze how the system, applied to a building in Manhattan, would harvest solar energy, capture CO2, and display environmental data.